Special Issue”Recent Developments in LC-MS of Algal Toxins: Present and Future Challenges”- Toxins

The combination of liquid chromatography with mass spectrometry (LC-MS) is a valuable tool for the determination of algal toxins contained at trace levels in complex matrices thanks to its high sensitivity, selectivity and ability to deal with the structural diversity and labile nature of the toxins. Targeted LC tandem MS (LC-MS/MS) approaches are already efficiently employed worldwide to monitor toxin distribution in the environment and in the food chain. At the same time, untargeted approaches based on  high resolution MS (LC-HRMS) have generally disclosed the presence of a much higher number and types of toxins and made straightforward elucidation of the gross structure of the unknowns based on the interpretation of their fragmentation patterns.

In view of the plethora of LC-MS/MS and LC-HRMS methods that have been developed so far, the need exists for critical reviews that, besides summarizing the methodologies for determination of each toxin-group, single out the main challenges to be addressed in the next future for marine, freshwater and fish-killing toxins. Collaborative efforts among scientists are strongly encouraged both in the field of the regulated toxins in EU and the emerging ones to build the rational basis for inter-laboratory validation trials, where needed. Original research articles reporting LC-MS based identification of emerging issues for water and food safety potentially associated with climate change as well as recent advancements in LC-MS data acquisition and treatment (On-line SPE-LC-MS, 2D-LC-MS, Metabolomics, among others) will be also included in this Special Issue.

More information can be found at: https://www.mdpi.com/journal/toxins/special_issues/lcms_Algal

Deadline for manuscript submissions is 31 December 2019

Guest Editors: Carmela Dell’Aversano and Luciana Tartaglione, Department of Pharmacy, University of Napoli Federico II


Postdoc researcher, Analytical and Environmental Chemistry (Natural Toxins) at Eawag

The Department of Environmental Chemistry (Uchem) of Eawag is offering a position for a Postdoctoral Researcher in Environmental and Analytical Chemistry.
Topic: Natural Toxins

The position is part of our research on natural toxins. Ecosystems and drinking water resources are not only vulnerable towards anthropogenic pollutants but also natural toxins. Bioactive compounds produced by aquatic organisms, such as cyanobacteria, are of particular concern since these are waterborne toxins directly released into surface waters. Cyanobacteria produce a diverse mixture of bioactive compounds beyond the well-known microcystins, yet the potential risk of many cyanobacterial metabolites remains mostly unknown.

The project is led by Dr Elisabeth Janssen (Uchem) in collaboration with Dr Colette vom Berg (Utox). The period of appointment for the Postdoctoral Researcher is 24 months, earliest starting date is January 2019 or as soon as the position can be adequately filled.
Closing date for applications is 15 November 2018.
Details and application form can be found here.