Harmful algal blooms formed by cyanobacteria (cyanoHABs) not only deteriorate ecosystem services but cause significant economic losses because of managing and treating drinking water and food supplies. Among those toxins, most prominent are the microcystins (and related peptides), i.e. by inhibiting eukaryotic protein phosphatases 1 and 2A of higher organisms. Intracellular toxic peptides can be released into the surrounding environment either through cell lysis or through active transport out of the cell.
One possibility to investigate cyanotoxins on the individual cell level is the so-called bioorthogonal labeling. In vivo labeling of cyanotoxins/peptides is based on the discovery of unspecific key enzymes involved in the synthesis pathway of those compounds which also can use non-natural functional groups as precursors. The resulting modified molecule is subsequently labeled by a fluorophore through a so-called click chemistry reaction. We will perform cyanotoxin/peptide labeling and high resolution imaging to localize, quantify and reveal inter/intracellular peptide storage and release using various isolates varying substantially in intra- and extracellular toxic peptide content (0-60% of the total content).
The tasks of this position will include (i) the integration of the data on cyanotoxin/peptide localization, and labeling of metabolites, (ii) experiments on strain-specific variation and stress-induced variation. The PhD candidate will be responsible for collecting the data on peptide localization using high resolution microscopy and further analysis using advanced imaging software, as well as to analyze the strain-specific and stress induced variation under controlled laboratory conditions.
Download the full call (pdf).
Further Information: Assoc. Prof. Dr. Rainer Kurmayer
Research Department for Limnology Mondsee, University of Innsbruck, Austria
For application please send a motivation letter together with a CV (in English) until 15 September 2019.
The BCCM-ULC cyanobacteria collection (University of Liege, Belgium) has an open position for a scientist/curator.
View details of the position here.
Contact: Dr. Annick Wilmotte, firstname.lastname@example.org .
The Department of Environmental Chemistry (Uchem) of Eawag is offering a position for a Postdoctoral Researcher in Environmental and Analytical Chemistry.
Topic: Natural Toxins
The position is part of our research on natural toxins. Ecosystems and drinking water resources are not only vulnerable towards anthropogenic pollutants but also natural toxins. Bioactive compounds produced by aquatic organisms, such as cyanobacteria, are of particular concern since these are waterborne toxins directly released into surface waters. Cyanobacteria produce a diverse mixture of bioactive compounds beyond the well-known microcystins, yet the potential risk of many cyanobacterial metabolites remains mostly unknown.
The project is led by Dr Elisabeth Janssen (Uchem) in collaboration with Dr Colette vom Berg (Utox). The period of appointment for the Postdoctoral Researcher is 24 months, earliest starting date is January 2019 or as soon as the position can be adequately filled.
Closing date for applications is 15 November 2018.
Details and application form can be found here.
The Fondazione Edmund Mach – Istituto Agrario di S. Michele all’Adige is looking for 1 temporary position for 30 months as Researcher (R4) in the field of aquatic ecology and metagenomic in the framework of the project ASP569 Eco-AlpsWater (250_CRI_AE).
The candidate will collaborate with the FEM researchers involved in the project Eco-AlpsWater during the activities of collection of environmental DNA (eDNA) samples, bioinformatic analysis of metagenomic data, statistical analysis of biological and environmental data. Moreover, the candidate will support the coordinator (N. Salmaso) in all the activities connected with the management of the project.
DEADLINE for applications: September 16, 2018
Call and application materials: https://www.fmach.it/eng/General-Services/Work-with-us
The São Paulo Research Foundation (FAPESP) is looking for a post-doc to develop research project at the Center for Research in Phycology, under the supervision of Dr Mutue Toyota Fujii, aiming to diagnose the seaweed biodiversity and to certify the identifications of scientific collections of the Institute of Botany, through morphological and molecular data.
See detaila about this positon in the Euraxess webpage.
Algenuity seeks an experienced and innovative strain engineering scientist/ molecular biologist to take a lead role in the design and conducting of laboratory-based genetic engineering projects in the field of microalgal biotechnology. This is a senior scientific position within the company, working closely with the CSO to ensure the timely delivery of Algenuity’s internal R&D projects and external research contracts.
Read the job description and required qualifications in the Euraxess page.
The aim of the project Eco-AlpsWater is to improve the traditional monitoring approaches used in the Alpine region (Water Framework Directive 2000/60/EC-EU WFD and, in Switzerland, the Water Protection Ordinance-WPO) with advanced and innovative DNA sequencing techniques such as metabarcoding. The new approach will make use of Next Generation Sequencing (NGS) to analyze environmental DNA in waterbodies (which allow rapid species identification at low costs, from fish to bacteria), and smart technologies (automation in data processing, data storage, information retrieval). Along with the identification of gaps in the monitoring approaches across the Alpine regions, the new technologies will allow to define improved experimental monitoring protocols to be applied in pilot areas partly linked to other ongoing alpine space projects (SPARE, Hymocares) and including large perialpine lakes as well as smaller waterbodies, and rivers.
The position will be financed for 3 years (30 working hours per week, 75 percent appointment) according to the collective labour agreement (Kollektivvertrag) of the Austrian Universities (2096.- Euro monthly salary, 14x per year). We are looking for a person holding a Master degree in Biology with experience in limnology (or comparable qualification), dedicated to apply metabarcoding approaches in fish communities (respectively other organism groups such as planktonic and benthic algae). Parts of the working activities (e.g. sampling and laboratory analysis) will be performed with partner organisations of the project, i.e. in Italy, Switzerland, France, Germany or Slovenia. Further activities will comprise metabarcoding data analysis, report writing, preparation of scientific manuscripts, as well as communication with project partners and observers. The registration of the PhD thesis in Biology at the University of Innsbruck and the administration within the new doctoral programme “Alpine Biology and Global Change” will be expected.
Further Information: Univ. Doz. Dr. Josef Wanzenböck & Assoc. Prof. Dr. Rainer Kurmayer, Research Department for Limnology Mondsee, University of Innsbruck
email: Josef.email@example.com; firstname.lastname@example.org. For application please send a motivation letter together with a CV (in English).
Download in pdf format.
From the description of this PhD position in Université Grenoble Alpes, France:
“How are photoperception and photosynthesis mechanistically interconnected? And how would photosynthetic organisms adapt to a stellar radiation with a spectral energy distribution different than this of earth? To address these questions, we will study the acclimation of the model photosynthetic organism Chlamydomonas reinhardtii, ancestor of higher plants, to stellar radiation of low and high intensities. We will assess the consequences of the exposure to this peculiar radiation at the level of genome-wide gene expression, photosynthetic activity, growth and cellular ultrastructure, using white visible light, blue and red illumination as reference conditions. Based on our results we are expecting to identify genes or gene-networks that are essential for the successful acclimation to the radiation of different light qualities. Using genome editing tools we will modify genes of interest to potentially generate mutants that will be adapted to type M radiation. The illumination with different light qualities will be achieved by use of LED panels. The expertise of IPAG will be valuable for the construction of a LED- panel mimicking the spectrum to type M radiation.”
Details of this PhD position can be found in the Euraxess page.
The Eawag postdoctoral fellowship position aims at offering outstanding young scientists with exciting research ideas the possibility for a two year research position at Eawag to strengthen their research career towards becoming independent scientists. Each year there is a call for a proposal submission, which includes a research plan, reference letters and a recommendation letter by one of the research department heads at Eawag.
Application deadline: April 9, 2018
Link to details of the position and application form.
The deadline for applications for the position as a researcher in marine and coastal lagoon ecology has been extended to 31 January 2018.
One post-graduate researcher position is available at the Foundation IMC International Marine Centre in Oristano, Sardinia, Italy (http://www.fondazioneimc.it/) in the field of sustainable management and conservation of Mediterranean coastal marine and lagoon environments.
We are seeking for a researcher with expertise in ecology of marine organisms and transitional aquatic environments. In particular, the successful candidate will have to evaluate the interactions between ecological processes and human activities in Mediterranean coastal-marine and lagoon environments assessing environmental quality of marine and transitional areas.
DUTIES AND RESPONSABILITIES
The successful applicant will be expected to:
- assess the impacts of fishing and aquaculture activities on marine and coastal lagoon environments;
- monitor and characterize benthic assemblages and fish communities in coastal marine and lagoon environment;
- assess biotic and abiotic factors affecting benthic assemblages.
The position’s description and application form can be found here.